HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

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Life Sciences, Biochemistry, Molecular Biology +10

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

Charles Y. Lin, Jakob Lovén, Peter B. Rahl et al. · Cell · 2012 · 1.6K citations · Full text

Medicine, Molecular Biology, Oncology +16

Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

Ola Landgren, Robert A. Kyle, Ruth M. Pfeiffer et al. · Blood · 2009 · 1.1K citations · Full text

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Keith D. Robertson, Slimane Ait‐Si‐Ali, Tomoki Yokochi et al. · Nature Genetics · 2000 · 942 citations

Life Sciences, Genetics, Molecular Biology +12

Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial

Jesús F. San Miguel, Vânia Hungria, Sung‐Soo Yoon et al. · The Lancet Oncology · 2014 · 788 citations

Medicine, Pharmacology, Pharmacotherapy +15