Concepedia
European Journal of Medicinal Chemistry · 2017 · 29 citations · 23 references
Open access
Medicinal ChemistrySolid Tumor CellsPotent Anticancer AgentsMedicineTumor TargetingAnti-cancer AgentCancer TreatmentPharmacologyRadiation OncologyMelampomagnolide BTumor BiologyDrug Discovery
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Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines
Larry Rubinstein, Robert H. Shoemaker, Kenneth D. Paull et al. · JNCI Journal of the National Cancer Institute · 1990 · 927 citations
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
Mónica L. Guzmán, Randall M. Rossi, Lilliana Karnischky et al. · Blood · 2005 · 673 citations · Full text
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
Mónica L. Guzmán, Randall M. Rossi, Sundar Neelakantan et al. · Blood · 2007 · 407 citations · Full text
Sesquiterpene Lactones Specifically Inhibit Activation of NF-κB by Preventing the Degradation of IκB-α and IκB-β
Steffen P. Hehner, Michael Heinrich, Peter M. Bork et al. · Journal of Biological Chemistry · 1998 · 341 citations · Full text
Inflammation, Cytokine, Anti-inflammatory +14
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF‐κB
Peter M. Bork, M. Lienhard Schmitz, Michaela Kuhnt et al. · FEBS Letters · 1997 · 326 citations · Full text