Steffen P. Hehner

The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.

Steffen P. Hehner, Thomas G. Hofmann, Wulf Dröge et al. · PubMed · 1999 · 386 citations

Antiinflammatory Sesquiterpene Lactone, Immunology, Inflammation +17

The Antiinflammatory Sesquiterpene Lactone Parthenolide Inhibits NF-κB by Targeting the IκB Kinase Complex

Steffen P. Hehner, Thomas G. Hofmann, Wulf Dröge et al. · The Journal of Immunology · 1999 · 355 citations · Full text

Inflammatory Lung Disease, Immunology, Immune Regulation +16

Sesquiterpene Lactones Specifically Inhibit Activation of NF-κB by Preventing the Degradation of IκB-α and IκB-β

Steffen P. Hehner, Michael Heinrich, Peter M. Bork et al. · Journal of Biological Chemistry · 1998 · 341 citations · Full text

Inflammation, Cytokine, Anti-inflammatory +14

Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB

Andreas Dumont, Steffen P. Hehner, Thomas G. Hofmann et al. · Oncogene · 1999 · 317 citations

Inflammation, Redox Signaling, Cell Signaling +11

The pro‐ or anti‐apoptotic function of NF‐κB is determined by the nature of the apoptotic stimulus

Barbara Kaltschmidt, Christian Kaltschmidt, Thomas G. Hofmann et al. · European Journal of Biochemistry · 2000 · 253 citations · Full text