Encapsulation of mangiferin in ordered mesoporous silica type SBA-15: synthesis and characterization

Abstract

SBA-15 ordered mesoporous silica were synthesized using the method reported by Zhao et al (1998 J. Am. Chem. Soc. 120 6024–36). The goal of this work is to study the encapsulation of mangiferin (MGN) into porous SBA-15. SBA–MGN composites were obtained from a mixture of SBA-15 and MGN. The structures of these materials were analyzed using different characterization techniques: differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), N2 adsorption–desorption measurement, transmission electron microscopy (TEM), absorbance spectra and electrochemical assay. The isotherms of the adsorption/desorption for SBA-15 and SBA–MGN are type IV, showing that the ordered mesoporous structure of SBA-15 was maintained even after the incorporation of MGN. The decrease in the value of the specific surface area and the reduction in pore volume confirmed the incorporation of MGN at the surface and in the pores of SBA-15. The incorporation of MGN in SBA-15 aims to increase the solubility of mangiferin.