ORAL CAVITY SQUAMOUS CELL CARCINOMA IN A CASE OF IFAP SYNDROME WITH CHRONIC MYELOID LEUKEMIA ON LONG TERM HYDROXYUREA: A RARE PRESENTATION

Abstract

We report a case of a patient in his early 30s’ who presented with an ulcero-proliferative growth over the left buccal mucosa , he was also on treatment for CML in blast crisis on Hydroxyurea and a known case of Ichthyosis Follicularis, Alopecia, and Photophobia (IFAP) syndrome. Though a working diagnosis of chloroma / Hydroxyurea induced erosive Lichen planus was suspected, the histopathological examination of the lesion was suggestive of Squamous cell Carcinoma. He was subsequently planned for palliative radiotherapy .