Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL

Sabah Kadri, Jimmy Lee, Carrie Fitzpatrick, Natalie Galanina, Madina Sukhanova, Girish Venkataraman, Shruti Sharma, Brad Long, Kristin Petras, Megan Theissen,

Blood Advances · 2017 · 132 citations · 40 references

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Abstract

mutation from that in the CLL leukemia cells. Collectively, these results provide insights into clonal evolution underlying ibrutinib relapse and prompt further investigation on genomic abnormalities that have clinical application potential.

References

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