MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Roger Stupp, Warren Mason, Martin J. van den Bent et al. · New England Journal of Medicine · 2005 · 21.6K citations · Full text

Medicine, Oncology, Radiation Oncology +12

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

Medicine, Cancer Biology, Oncology +16

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

Heidi Phillips, Samir Kharbanda, Ruihuan Chen et al. · Cancer Cell · 2006 · 3.2K citations · Full text

Medicine, Neuroscience, Oncology +16

PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

Anne-Marie Bleau, Dolores Hambardzumyan, Tatsuya Ozawa et al. · Cell stem cell · 2009 · 801 citations · Full text

Medicine, Cancer Biology, Oncology +17

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

Wynand P. Roos, Luís F.Z. Batista, Steffen C. Naumann et al. · Oncogene · 2006 · 497 citations

Medicine, Oncology, Pharmacology +14