microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1

Abstract

Taken together, we characterized the miRNA regulation in L. pneumophila infection with regard to MyD88 signaling and identified NTAN1 as a target of miR-125a-3p. This finding unravels a yet unknown feature of Legionella-host cell interaction, potentially relevant for new treatment options.