F1000Research · 2017 · 379 citations · 40 references
MedicineNeurological SurgeryNeurologyCerebrovascular NeurosurgeryCerebrovascular SurgeryVascular SurgeryAcute Ischemic StrokeAcute Stroke CareAcute Stroke ManagementCerebrovascular DiseaseStrokeStroke SurgeryAcute Ischemic Stroke InterventionAcute Ischemic Stroke ManagementAcute Ischemic Stroke SurgeryAcute Ischemic Stroke TreatmentCirculationEndovascular Intervention CareEndovascular Stroke Treatment
In recent years, several landmark trials have transformed acute ischemic stroke care. The most dramatic results from the field of acute endovascular intervention demonstrate unequivocal benefit for a select group of patients with moderate to severe deficits presenting within 7 hours from onset and with occlusions of proximal arteries in the anterior circulation. In addition, technological advances and workflow efficiencies have facilitated more rapid delivery of acute stroke interventions. This review provides an overview of recent advances in the management of acute ischemic stroke.
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Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
Werner Hacke, Markku Kaste, Erich Bluhmki et al. · New England Journal of Medicine · 2008 · 6.6K citations · Full text
A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
Olvert A. Berkhemer, Puck Fransen, Debbie Beumer et al. · New England Journal of Medicine · 2014 · 6.6K citations · Full text
Medicine, Neurology, Neurosurgery +14
Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection
Bruce Campbell, Peter Mitchell, Timothy Kleinig et al. · New England Journal of Medicine · 2015 · 5.8K citations · Full text
Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke
Jeffrey L. Saver, Mayank Goyal, Alain Bonafé et al. · New England Journal of Medicine · 2015 · 5.1K citations · Full text