TRIB3 downregulation enhances doxorubicin-induced cytotoxicity in gastric cancer cells

TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death

Nobumichi Ohoka, Satoshi Yoshii, Takayuki Hattori et al. · The EMBO Journal · 2005 · 992 citations · Full text

TRB3: A <i>tribbles</i> Homolog That Inhibits Akt/PKB Activation by Insulin in Liver

Keyong Du, Stephan Herzig, Rohit Kulkarni et al. · Science · 2003 · 829 citations

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis

Heiko Müller, Adrian P. Bracken, Richard Vernell et al. · Genes & Development · 2001 · 743 citations · Full text

Signal Transduction, Developmental Biology, Signaling Pathway +14

Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

Gi-Bang Koo, Michael K. Morgan, Da‐Gyum Lee et al. · Cell Research · 2015 · 485 citations · Full text

Rip3 Expression, Oncology, Methylation-dependent Loss +9

Direct coupling of the cell cycle and cell death machinery by E2F

Zaher Nahlé, Julia Polakoff, Ramana V. Davuluri et al. · Nature Cell Biology · 2002 · 420 citations

Signal Transduction, Cell Regulation, Cell Division +12