Concepedia

Design and in vitro biological evaluation of substituted chalcones synthesized from nitrogen mustards as potent microtubule targeted anticancer agents

X. Janet Sabina, Gunasekaran Velmurugan, Manoharan Muthu Tamizh, A. Nityananda Shetty

New Journal of Chemistry · 2017 · 24 citations · 58 references

DOI

Concepts

Abstract

Six chalcones were synthesized and their structures determined by single crystal X-ray diffraction studies. They exhibited enhanced anticancer activity and tubulin inhibition.

References

58

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