Synergistic and targeted drug delivery based on nano-CeO₂ capped with galactose functionalized pillar[5]arene via host–guest interactions

Abstract

A smart drug delivery system based on porous CeO₂ nano-rods (CeONRs) capped with galactose functionalized pillar[5]arene via host-guest interactions has been constructed, which showed GSH-responsiveness, synergism with anticancer drugs and cancer targeting ability resulting from its disulphide unit, ceria properties and galactose units, respectively.