Gastric Duplication Complicated by Malignant Transformation in Adults: Report of Three Cases

Abstract

Gastric duplication anomaly is an uncommon congenital disease, mostly reported in children. Malignant transformation of the duplication lesion is extremely rare, with only 11 cases reported in the English literature. Here we report three cases of early cancer found in gastric duplications or the adjacent gastric wall. Out of these three cases, one is an early cancer arising from the duplication lesion, one from the gastric wall and another form both. To the best of our knowledge, early cancer arising from both the duplication cyst and the adjacent wall is first reported. Once detected gastric duplication, surgical resection is recommended because of its potential for malignant transformation.