<i>ADAMTSL5</i> and <i>CDH11</i> : putative epigenetic markers for therapeutic resistance in acute lymphoblastic leukemia

Abstract

Chemoresistant B-ALL patients are associated with increased methylation in ADAMTSL5 and CDH11. These findings need to be validated in a larger group of patients, and the functional biological and prognostic significance of differential methylation needs to be studied further.