Concepedia

Glycan-decorated HPMA copolymers as high-affinity lectin ligands

Pavla Bojarová, Petr Chytil, Barbora Mikulová, Ladislav Bumba, Rafał Konefał, Helena Pelantová, Jana Krejzová, Kristýna Slámová, Lucie Petrásková, Lenka Kotrchová,

Polymer Chemistry · 2017 · 34 citations · 22 references

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Concepts

Abstract

New conjugates of<italic>N</italic>-(2-hydroxypropyl) methacrylamide (HPMA) copolymers tethered with chitooligosaccharidic epitopes of varying lengths are potent ligands of wheat germ agglutinin, reaching subnanomolar binding affinities.

References

22

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 12.9K citations

, , +17

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 9.3K citations · Full text

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.4K citations

, , +15

Reversible Addition−Fragmentation Chain Transfer Polymerization:  End Group Modification for Functionalized Polymers and Chain Transfer Agent Recovery

Sébastien Perrier, Pittaya Takolpuckdee, Craig A. Mars · Macromolecules · 2005 · 476 citations

, , +14

The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrate for lysozyme

J.A. Rupley · Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides · 1964 · 476 citations

, , +7