Proteomic analysis of microparticles isolated from malaria positive blood samples

Abstract

A great number of proteins were observed to be carried in the microparticles (MPs) from malaria samples and culture supernatant compared to controls. The greater loss of haemoglobin from erythrocytes via MPs from malaria patients could serve as the initiation and progression of anaemia in <i>P.falciparum</i> infection. Also while some proteins were upregulated in circulating MPs in malaria samples, others were down regulated.