Concepedia

Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway

Yujing Zhang, Fang Xiao, Xinmin Liu, Kaihua Liu, Xiaoxin Zhou, Caigao Zhong

Toxicology in Vitro · 2017 · 68 citations · 33 references

DOI

Concepts

References

33

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

Stefan J. Marciniak, Chi Young Yun, Seiichi Oyadomari et al. · Genes & Development · 2004 · 2K citations · Full text

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PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

Tom Verfaillie, Noemí Rubio, Abhishek D. Garg et al. · Cell Death and Differentiation · 2012 · 838 citations · Full text

, , +14

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

Jyoti Malhotra, Hongzhi Miao, Kezhong Zhang et al. · Proceedings of the National Academy of Sciences · 2008 · 672 citations · Full text

, , +17

Chromium, nickel and welding.

PubMed · 1990 · 448 citations · Full text

, , +8

Mitochondria-mediated apoptosis in mammals

Shunbin Xiong, Tianyang Mu, Guowen Wang et al. · Protein & Cell · 2014 · 399 citations · Full text

, , +17