β-Hydroxybutyrate Boosts Mitochondrial and Neuronal Metabolism but is not Preferred Over Glucose Under Activated Conditions

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

Owen W. Griffith, A Meister · Journal of Biological Chemistry · 1979 · 1.7K citations · Full text

Life Sciences, Pharmacology, Biochemical Pharmacology +13

Fine structural localization of glutamine synthetase in astrocytes of rat brain

Michael D. Norenberg, Antonio Martinez-Hernandez · Brain Research · 1979 · 1.3K citations

Medicine, Neurobiology, Neuroscience +16

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

William C. Hallows, Susan Lee, John M. Denu · Proceedings of the National Academy of Sciences · 2006 · 794 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

Alexander S. Hebert, Kristin E. Dittenhafer‐Reed, Wei Yu et al. · Molecular Cell · 2012 · 641 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

Matthew J. Rardin, Jason M. Held, Michael P. Cusack et al. · Proceedings of the National Academy of Sciences · 2013 · 451 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11