Indole-TEMPO conjugates alleviate ischemia-reperfusion injury via attenuation of oxidative stress and preservation of mitochondrial function

Cardiac reperfusion damage prevented by a nitroxide free radical.

Dan Gelvan, Paul Saltman, Saul R. Powell · Proceedings of the National Academy of Sciences · 1991 · 181 citations

Life Sciences, Cardiology, Physiology +14

Mitochondrial Targeting of Selective Electron Scavengers:  Synthesis and Biological Analysis of Hemigramicidin−TEMPO Conjugates

Peter Wipf, Jingbo Xiao, Jianfei Jiang et al. · Journal of the American Chemical Society · 2005 · 154 citations

Pharmacy, Medicinal Chemistry, Pharmaceutics +15

The mechanisms and strategies to protect from hepatic ischemia-reperfusion injury.

Jing Li, R.-J. Li, Guoyue Lv et al. · PubMed · 2015 · 119 citations

Life Sciences, Immunology, Pathobiology +17

New Rhodamine Nitroxide Based Fluorescent Probes for Intracellular Hydroxyl Radical Identification in Living Cells

Nazmiye Yapici, Steffen Jockusch, Alberto Moscatelli et al. · Organic Letters · 2011 · 109 citations

Natural Sciences, Biochemistry, Chemistry +17

Treatment With a Novel Hemigramicidin-TEMPO Conjugate Prolongs Survival in a Rat Model of Lethal Hemorrhagic Shock

Carlos Macías, Jeffrey W Chiao, Jingbo Xiao et al. · Annals of Surgery · 2007 · 88 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15