Concepedia

Publication | Open Access

Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice

DOIFull Paper Access

96

Citations

42

References

2017

Year

Idoia García‐Ramírez, Saber Tadros, Inés González‐Herrero, Alberto Martín‐Lorenzo, Guillermo Rodríguez-Hernández, Dalia Moore, Lucía Ruiz-Roca, Óscar Blanco, Diego Alonso‐López, Javier De Las Rivas,
Blood

Abstract

Key Points Crebbp inactivation perturbs B-cell development, but cooperates with Bcl2 overexpression to promote lymphoma. Transcriptional and epigenetic signatures of Crebbp loss implicate Myc in disease etiology.

References

YearCitations

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