Identification of forced degradation products of tedizolid phosphate by liquid chromatography/electrospray ionization tandem mass spectrometry

The Site of Action of Oxazolidinone Antibiotics in Living Bacteria and in Human Mitochondria

Karen L. Leach, Steven Swaney, Jerry R. Colca et al. · Molecular Cell · 2007 · 275 citations · Full text

Life Sciences, Microbiology, Pharmacology +8

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

Karen Joy Shaw, Susan M. Poppe, Ronda D. Schaadt et al. · Antimicrobial Agents and Chemotherapy · 2008 · 180 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

<i>In Vivo</i> Pharmacodynamics of Torezolid Phosphate (TR-701), a New Oxazolidinone Antibiotic, against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Strains in a Mouse Thigh Infection Model

Arnold Louie, Weiguo Liu, Robert Kulawy et al. · Antimicrobial Agents and Chemotherapy · 2011 · 89 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

<i>In Vitro</i> Activity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated Skin and Skin Structure Infections

Philippe Prokocimer, Paul Bien, Carisa DeAnda et al. · Antimicrobial Agents and Chemotherapy · 2012 · 87 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Tedizolid Population Pharmacokinetics, Exposure Response, and Target Attainment

Shawn D. Flanagan, Julie Passarell, Qin Lü et al. · Antimicrobial Agents and Chemotherapy · 2014 · 86 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16