Imetelstat, a telomerase inhibitor, differentially affects normal and malignant megakaryopoiesis

Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis

Nveed Chaudhary, Gerald J. Roth, Frank Hilberg et al. · European Respiratory Journal · 2007 · 393 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis

Ayalew Tefferi, Terra L. Lasho, Kebede H. Begna et al. · New England Journal of Medicine · 2015 · 322 citations · Full text

Medicine, Hematology, Pharmacology +13

The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth

Calin O. Marian, Steve K. Cho, Brian McEllin et al. · Clinical Cancer Research · 2010 · 223 citations · Full text

Medicine, Oncology, Pharmacology +17

Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia

Ruben A. Mesa, Curtis A. Hanson, S. Vincent Rajkumar et al. · Blood · 2000 · 212 citations

Medicine, Hematology, Pathology +16

Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis

Stefan O. Ciurea, Delwin Merchant, Nadim Mahmud et al. · Blood · 2007 · 211 citations · Full text

Medicine, Cell Biology, Hematology +14