Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and <em>Drosophila melanogaster</em>

Abstract

The present study suggests that ZnO NPs induced significant oxidative stress-related cytotoxicity and genotoxicity in human lung fibroblasts in vitro and in <i>D. melanogaster</i> in vivo. More extensive studies would be needed to verify the safety issues related to increased usage of ZnO NPs by consumers.