JAMA Neurology · 2017 · 186 citations · 32 references
This study confirms the role of NFL as a biomarker in ALS. Elevation in NFL levels in patients with upper motor neuron involvement and FTD might reflect the corticospinal tract degeneration. Low NFL levels in patients with lower motor neuron signs might be a prognostic indicator of milder phenotypes of disease.
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pROC: an open-source package for R and S+ to analyze and compare ROC curves
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Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
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Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases
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