Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

Alan H. Bryce, Jan B. Egan, Mitesh J. Borad, A. Keith Stewart, Grzegorz S. Nowakowski, Asher Chanan‐Khan, Mrinal M. Patnaik, Stephen M. Ansell, Michaela S. Banck, Steven I. Robinson,

Oncotarget · 2017 · 78 citations · 14 references

DOIFull text

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Abstract

Treatment decisions driven by tumor genomic analysis can lead to significant clinical benefit in a minority of patients. The success of genomically driven therapy depends both on access to drugs and robustness of bioinformatics analysis. While novel clinical trial designs are increasing the utility of genomic testing, robust data sharing of outcomes is needed to optimize clinical benefit for all patients.

References

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