Oncotarget · 2017 · 78 citations · 14 references
Treatment decisions driven by tumor genomic analysis can lead to significant clinical benefit in a minority of patients. The success of genomically driven therapy depends both on access to drugs and robustness of bioinformatics analysis. While novel clinical trial designs are increasing the utility of genomic testing, robust data sharing of outcomes is needed to optimize clinical benefit for all patients.
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Paul A. Harris, Robert Taylor, Robert J. Thielke et al. · Journal of Biomedical Informatics · 2008 · 48.8K citations · Full text
Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth
Rajen Mody, Yi-Mi Wu, Robert J. Lonigro et al. · JAMA · 2015 · 408 citations · Full text
Mitesh J. Borad, Mia D. Champion, Jan B. Egan et al. · PLoS Genetics · 2014 · 334 citations · Full text
Fgfr Inhibitors, Pathology, Sporadic Intrahepatic Cholangiocarcinoma +19