<scp>AMP</scp> ‐activated protein kinase ( <scp>AMPK</scp> ) activator <scp>A</scp> ‐769662 increases intracellular calcium and <scp>ATP</scp> release from astrocytes in an <scp>AMPK</scp> ‐independent manner

Abstract

AMPK is required to maintain basal eATP levels but is not required for A-769662-induced increases in eATP. A-769662 (>50 μM) enhanced intracellular calcium levels leading to ATP release in an AMPK and purinergic receptor independent pathway.