Association Between Matrix Metalloproteinase-9 and Worsening Heart Failure Events in Patients with Chronic Heart Failure

Abstract

MMP-9 and TIMP-1 levels correlate with the severity of chronic HF. MMP-9 is a strong predictor of HF events, suggesting that a disparity between MMP-9 and TIMP-1 levels and increased MMP-9 levels may help predict HF events.