Aptasensors for the selective detection of alpha-synuclein oligomer by colorimetry, surface plasmon resonance and electrochemical impedance spectroscopy

Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles

Robert Elghanian, James J. Storhoff, Robert C. Mucic et al. · Science · 1997 · 4.4K citations

Engineering, Biotechnology, Molecular Biology +17

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

Maria Grazia Spillantini, R. Anthony Crowther, Ross Jakes et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

Kelly A. Conway, Seung‐Jae Lee, Jean‐Christophe Rochet et al. · Proceedings of the National Academy of Sciences · 2000 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +17

In vivo demonstration that α-synuclein oligomers are toxic

Beate Winner, Roberto Jappelli, Samir K. Maji et al. · Proceedings of the National Academy of Sciences · 2011 · 1.5K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Aptamer-based biosensors

Shiping Song, Lihua Wang, Jiang Li et al. · TrAC Trends in Analytical Chemistry · 2007 · 1.4K citations