Enantioselective conjugate addition of hydroxylamines to α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal Rh(<scp>iii</scp>) complex

Abstract

A highly efficient chiral-at-metal Rh(<sc>iii</sc>) complex catalyzed asymmetric aza-Michael addition was developed, affording<italic>N</italic>-protected β-amino acid derivatives with excellent enantioselectivity.