MedChemComm · 2017 · 33 citations · 37 references
Life SciencesGeneticsMicrobiologyComparative GenomicsGenomicsMicrobial GeneticsBiosynthetic Gene ClustersMicrobial Genome StructureMicrobial Natural Product BiosynthesisActinomycete Secondary MetabolismBiosynthetic Gene Cluster AnalysisBiosynthetic Gene Cluster EvolutionMicrobial Genome-encoded BiosynthesisSecondary Metabolite Gene ClustersSecondary Metabolites
is that it contains two cytochrome P450 enzymes, which likely catalyze three crosslinking reactions. These findings set the stage for examining the biosynthesis of kistamicin and its unusual indole-phenol crosslink in the future.
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