CMAJ Open · 2017 · 39 citations · 6 references
MedicinePreventive MedicinePublic Health NutritionDisease PreventionHealth Services ResearchHuman NutritionDisease ControlPopulation ScreeningVitamin DVitamin D DeficiencyVitamin D DisordersCost Savings AnalysisCost Savings EvaluationInterrupted Series AnalysisInterrupted Time Series DesignSerum 25-Hydroxyvitamin D StatusVitamin D AssessmentVitamin D Deficiency ScreeningVitamin Deficiency Prevention
BACKGROUND: We describe the implementation of an intervention in Alberta in support of the Choosing Wisely Canada recommendation against population screening for vitamin D deficiency (as determined by serum total 25-hydroxyvitamin D testing). We hypothesized that the introduction of a specialized requisition for vitamin D testing would reduce the annual number of vitamin D tests performed. METHODS: We performed a cross-sectional observational study that included all vitamin D tests ordered in Alberta between Apr. 1, 2015, and Mar. 31, 2016. There were no exclusion criteria. A special requisition for ordering vitamin D tests in Alberta was introduced on Apr. 1, 2015. Using an interrupted time series model, we compared predicted versus observed vitamin D test volumes for the 12-month period following the introduction of the new requisition. The sole outcome measure was the monthly change in volume of vitamin D testing. In addition, we calculated any cost savings as a result of reduced testing. RESULTS: Over the first 12 months of the intervention, there was a reduction in the number of tests ordered from a predicted 342 477 tests to 29 525 tests (91.4% reduction). This decrease represented a direct spending decrease of Can$938 856-$1 564 760 per year in Alberta. INTERPRETATION: A provincially led implementation of a Choosing Wisely Canada recommendation resulted in a large and sustained reduction in serum total 25-hydroxyvitamin D testing in Alberta. This study shows that provincially led interventions based on Choosing Wisely Canada recommendations can result in substantial reductions in laboratory tests.
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On a measure of lack of fit in time series models
Greta M. Ljung, George E. P. Box · Biometrika · 1978 · 6K citations
Eric Morgen, Christopher Naugler · American Journal of Clinical Pathology · 2015 · 69 citations · Full text
Public Health, Population Health Sciences, Public Health Informatics +17
Interventions to Educate Family Physicians to Change Test Ordering
Roger E. Thomas, Marcus Vaska, Christopher Naugler et al. · Academic Pathology · 2016 · 18 citations · Full text