Journal of the National Comprehensive Cancer Network · 2016 · 661 citations · 43 references
Life SciencesGeneticsOncologyCancer GeneticsGenetic CounselingMedical GeneticsBreast Cancer Risk AssessmentGenetic Risk AssessmentGermline Cancer PredispositionHereditary Cancer SyndromesHereditary Gynecologic Cancer SyndromesOvarian CancerBreast Risk AssessmentGenetic TestingHereditary Breast Cancer Risk AssessmentHereditary Breast Cancer SyndromeHereditary Cancer RiskHereditary Cancer ScreeningHereditary Ovarian Cancer SyndromeInherited Cancer Risk
The NCCN Clinical Practice Guidelines in Oncology for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling for hereditary cancer syndromes and risk management recommendations for patients who are diagnosed with a syndrome. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer. The NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations. The NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding risk management for carriers of moderately penetrant genetic mutations associated with breast and/or ovarian cancer.
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Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk
Douglas F. Easton, Paul D.P. Pharoah, Antonis C. Antoniou et al. · New England Journal of Medicine · 2015 · 937 citations · Full text
Life Sciences, Genetics, Oncology +17
Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome
Nicholas Hearle, Valerié Schumacher, Fred H. Menko et al. · Clinical Cancer Research · 2006 · 853 citations
Inherited Mutations in Women With Ovarian Carcinoma
Barbara M. Norquist, Maria I. Harrell, Mark F. Brady et al. · JAMA Oncology · 2015 · 764 citations · Full text
Fergus J. Couch, Steven N. Hart, Priyanka Sharma et al. · Journal of Clinical Oncology · 2014 · 684 citations · Full text
Life Sciences, Genetics, Oncology +17