Biocompatible CuS-based nanoplatforms for efficient photothermal therapy and chemotherapy in vivo

Abstract

) by the Stober method, and further loaded with anticancer drug doxorubicin (DOX). The nanocomposites obtained were named CuS@MSN-DOX. The infrared thermal imaging of CuS@MSN-DOX demonstrated its favorable photothermal efficacy. The potential of CuS@MSN-DOX utilized as a multifunctional platform for combined PPT and chemotherapy was exploited both at the cell level and in a mice model. The result demonstrated that CuS@MSN-DOX was endowed with the synergistic effect of chemo-photothermal therapy, which confirmed that it is a promising candidate for combined therapy of cancer.