Science Translational Medicine · 2017 · 330 citations · 33 references
MedicineCancer BiologyImmunologyBiomedical ImagingCancer ImmunologyTumor ImmunologyCancer ImmunotherapyImmunotherapy For Brain TumorsMolecular Imaging In OncologyNeuro-oncology ImagingT Cell Responses To TumorsTumor ImagingGlioblastoma ImmunotherapyGlioblastoma Targeted TherapyOncologic Pet ImagingReporter Gene SystemsT Cell-based ImmunotherapyTargeted Immunotherapy
F]FHBG imaging was safe and enabled the longitudinal imaging of T cells stably transfected with a PET reporter gene in patients. Further optimization of this imaging approach for monitoring in vivo cell trafficking should greatly benefit various cell-based therapies for cancer.
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