The Neuropeptide Orexin-A Inhibits the GABAA Receptor by PKC and Ca2+/CaMKII-Dependent Phosphorylation of Its β1 Subunit

The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

Luı́s de Lecea, Thomas S. Kilduff, Christelle Peyron et al. · Proceedings of the National Academy of Sciences · 1998 · 3.8K citations

Hypothalamic Circuits, Hypothalamus-specific Mrna, Gastrointestinal Peptide Hormone +17

Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

Christelle Peyron, Devin K. Tighe, Anthony N. van den Pol et al. · Journal of Neuroscience · 1998 · 3.5K citations · Full text

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Christelle Peyron, Juliette Faraco, William M. Rogers et al. · Nature Medicine · 2000 · 2.1K citations

Neurophysiology, Medicine, Neurotransmitter +12

Reduced Number of Hypocretin Neurons in Human Narcolepsy

Thomas C. Thannickal, Robert Y. Moore, Robert Nienhuis et al. · Neuron · 2000 · 2.1K citations · Full text

Neurophysiology, Reduced Number, Physiology +7

Differential expression of orexin receptors 1 and 2 in the rat brain

Jacob Marcus, Carl Aschkenasi, Charlotte E. Lee et al. · The Journal of Comparative Neurology · 2001 · 1.6K citations

Synaptic Transmission, Neurotransmitter, Neurotransmission +22