Concepedia

The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1β

Noha S. Farag, U. Breitinger, Mohamed El-Azizi, Hans‐Georg Breitinger

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2016 · 37 citations · 26 references

DOI

Concepts

References

26

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

, , +13

Proton-sensing G-protein-coupled receptors

Marie‐Gabrielle Ludwig, M. Vanek, Danilo Guerini et al. · Nature · 2003 · 742 citations

Influenza virus activates inflammasomes via its intracellular M2 ion channel

Takeshi Ichinohe, Iris K. Pang, Akiko Iwasaki · Nature Immunology · 2010 · 621 citations

, , +14

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κB

Guozhong Gong, Gulam Waris, Rasheeda Tanveer et al. · Proceedings of the National Academy of Sciences · 2001 · 577 citations · Full text

, , +17

The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

Stephen Griffin, Lucy Beales, Dean Clarke et al. · FEBS Letters · 2002 · 485 citations

, , +17