In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia

Stephen Francis, Amelia D. Wallace, George A. Wendt, Linlin Li, Fenyong Liu, Lee W. Riley, Scott C. Kogan, Kyle M. Walsh, Adam J. de Smith, Gary V. Dahl,

Blood · 2016 · 86 citations · 19 references

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Abstract

= .0016). Risk was more pronounced in Hispanics (OR=5.90, CI=1.89-25.96) than in non-Hispanic whites (OR=2.10 CI= 0.69-7.13). This is the first study to suggest that congenital CMV infection is a risk factor for childhood ALL and is more prominent in Hispanic children. Further investigation of CMV as an etiologic agent for ALL is warranted.

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