Concepedia

IL-4 mRNA Is Downregulated in the Liver of Pancreatic Cancer Patients Suffering from Cachexia

Olga Prokopchuk, Jürgen M. Steinacker, Ulrich Nitsche, Stephanie Otto, Jeannine Bachmann, Elaine C. Schubert, Marc E. Martignoni

Nutrition and Cancer · 2016 · 24 citations · 26 references

DOI

Abstract

We speculate that suppression of IL-4 is involved in cancer cachexia, although the exact mechanisms have to be further elucidated.

References

26

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index

Lisa Martin, Laura Birdsell, Neil Macdonald et al. · Journal of Clinical Oncology · 2013 · 2.5K citations

Definition of cancer cachexia: effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis

Kenneth C.H. Fearon, Anne Coble Voss, Deborah S. Hustead · American Journal of Clinical Nutrition · 2006 · 770 citations · Full text

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Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

Suman K. Das, Sandra Eder, Silvia Schauer et al. · Science · 2011 · 573 citations

IL-4 Acts as a Myoblast Recruitment Factor during Mammalian Muscle Growth

Valerie Horsley, Katie M. Jansen, Stephen T. Mills et al. · Cell · 2003 · 485 citations · Full text

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