Concepedia

A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

Mary Dasso, Takashi Seki, Yoshiaki Azuma, T. Ohba, T. Nishimoto

The EMBO Journal · 1994 · 140 citations · 44 references

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44

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

Kun‐Liang Guan, J.E. Dixon · Analytical Biochemistry · 1991 · 1.8K citations

, , +16

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

Mary Shannon Moore, Günter Blobel · Nature · 1993 · 763 citations

, , +11

Inhibition of NIH 3T3 Cell Proliferation by a Mutant <i>ras</i> Protein with Preferential Affinity for GDP

Larry A. Feig, Geoffrey M. Cooper · Molecular and Cellular Biology · 1988 · 755 citations · Full text

, , +17

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

F. Ralf Bischoff, Herwig Ponstingl · Nature · 1991 · 719 citations

, , +8

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

J. Julian Blow, Ronald A. Laskey · Cell · 1986 · 619 citations

, , +10