Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

Adeline Bertola, Stephanie Mathews, Sung Hwan Ki et al. · Nature Protocols · 2013 · 1.2K citations · Full text

Medicine, Neurobiology, Neuroscience +12

Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

Yu Li, Kimberly Wong, Amber Giles et al. · Gastroenterology · 2013 · 283 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice

P Czochra, Borut Klopcic, Erik Meyer et al. · Journal of Hepatology · 2006 · 243 citations

Medicine, Molecular Biology, Pathology +15

Deletion of SIRT1 From Hepatocytes in Mice Disrupts Lipin-1 Signaling and Aggravates Alcoholic Fatty Liver

Huquan Yin, Ming Hu, Xiaomei Liang et al. · Gastroenterology · 2013 · 213 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans

Ming-jiang Xu, Yan Cai, Hua Wang et al. · Gastroenterology · 2015 · 144 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14