Concepedia

Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate

Ramesh Soundararajan, Kenji Sasaki, Lisa Godfrey, Uchechukwu Odunze, Nancy Fereira, Andreas G. Schätzlein, Ijeoma F. Uchegbu

International Journal of Pharmaceutics · 2016 · 15 citations · 28 references

DOI

Concepts

References

28

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

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THE RATE OF SOLUTION OF SOLID SUBSTANCES IN THEIR OWN SOLUTIONS.

Arthur A. Noyes, W. R. Whitney · Journal of the American Chemical Society · 1897 · 1.9K citations

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What is the True Solubility Advantage for Amorphous Pharmaceuticals?

Bruno C. Hancock, Michael Parks · Pharmaceutical Research · 2000 · 1.3K citations

, , +14

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 880 citations

, , +15

Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells.

Kazuyuki Yusa, T Tsuruo · PubMed · 1989 · 367 citations

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