Concepedia

An efficient CuI/DBU-catalyzed one-pot protocol for synthesis of 1,4-disubstituted 1,2,3-triazoles

Yuqin Jiang, Xingfeng Li, Yaru Zhao, Shuhong Jia, Mingrui Li, Zhiqi Zhao, Ruili Zhang, Wei Li, Weiwei Zhang

RSC Advances · 2016 · 16 citations · 34 references

DOI

Concepts

Abstract

A convenient CuI/DBU catalyzed one-pot method has been developed for the synthesis of 1,4-disubstituted 1,2,3-triazoles from aryl iodides, sodium azide and phenylacetaldehyde derivatives or from aryl iodides, sodium azide and alkynes in DMSO.

References

34

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

, , +8

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

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One-Pot Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from In Situ Generated Azides

Alina K. Feldman, Benoît Colasson, Valery V. Fokin · Organic Letters · 2004 · 344 citations

, , +11

1,2,3‐Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3‐Dipolar Cycloadditions

Antonino Lauria, Riccardo Delisi, Francesco Mingoia et al. · European Journal of Organic Chemistry · 2014 · 342 citations

, , +14

Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3‐Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a “Green” Solvent

Hashem Sharghi, Reza Khalifeh, Mohammad Mahdi Doroodmand · Advanced Synthesis & Catalysis · 2009 · 309 citations

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