Concepedia

Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers

Zhou Meng, Sylvain J. Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens, Joe Bentz

Drug Metabolism and Disposition · 2016 · 13 citations · 23 references

DOI

Concepts

References

23

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

Junichi Kamiie, Sumio Ohtsuki, Ryo Iwase et al. · Pharmaceutical Research · 2008 · 479 citations

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Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

Janice Hunter, Mark A. Jepson, T Tsuruo et al. · Journal of Biological Chemistry · 1993 · 367 citations · Full text

, , +17

Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

Rose Hayeshi, Constanze Hilgendorf, Per Artursson et al. · European Journal of Pharmaceutical Sciences · 2008 · 264 citations

, , +14

P-Glycoprotein (P-gp) Mediated Efflux in Caco-2 Cell Monolayers: The Influence of Culturing Conditions and Drug Exposure on P-gp Expression Levels

Pascale Anderle, Eva Niederer, Werner Rubas et al. · Journal of Pharmaceutical Sciences · 1998 · 230 citations

, , +8

Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors

N. J. Proctor, Geoffrey T. Tucker, Amin Rostami‐Hodjegan · Xenobiotica · 2004 · 219 citations

, , +17