Concepedia

Dual encapsulation of hydrophobic and hydrophilic drugs in PLGA nanoparticles by a single-step method: drug delivery and cytotoxicity assays

Laura Español, Ane Larrea, Vanesa Andreu, Gracia Mendoza, Manuel Arruebo, Víctor Sebastián, María Segunda Aurora‐Prado, Érika Rosa Maria Kedor-Hackmann, María Inés Rocha Miritello Santoro, Jesús Santamarı́a

RSC Advances · 2016 · 83 citations · 51 references

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Concepts

Abstract

Dual drug encapsulation in biodegradable nanoparticles is always challenging and often requires strenuous optimization of the synthesis–encapsulation processes.

References

51

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles

Shanta Dhar, Frank Gu, Róbert Langer et al. · Proceedings of the National Academy of Sciences · 2008 · 990 citations · Full text

, , +14

PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution

Rubiana Mara Mainardes, Raul Cesar Evangelista · International Journal of Pharmaceutics · 2005 · 486 citations

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Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D,L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior

Toshiyuki Niwa, Hirofumi Takeuchi, Tomoya Hino et al. · Journal of Controlled Release · 1993 · 483 citations · Full text

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Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery

Dong‐Hwan Kim, David C. Martin · Biomaterials · 2006 · 428 citations

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Haloperidol-loaded PLGA nanoparticles: Systematic study of particle size and drug content

Avinash Budhian, Steven J. Siegel, Karen I. Winey · International Journal of Pharmaceutics · 2006 · 415 citations

, , +17