Improved Bone Regeneration With Multiporous PLGA Scaffold and BMP-2–Transduced Human Adipose-Derived Stem Cells by Cell-Permeable Peptide

Abstract

The result demonstrates that transferring BMP-2 promotes the osteogenic differentiation of ADSCs and enhances bone regeneration. Under limitation of this study, genetic modification of ADSCs with BMP-2 could be adopted in clinical application.