Concepedia

Triggering of Erythrocyte Cell Membrane Scrambling by Emodin

Morena Mischitelli, Mohamed Jèmaà, Mustafa Almasry, Caterina Faggio, Florian Läng

Cellular Physiology and Biochemistry · 2016 · 36 citations · 121 references

DOIFull text

Open access

Abstract

Emodin triggers phospholipid scrambling of the erythrocyte cell membrane, an effect at least in part due to stimulation of Ca2+ entry and paralleled by oxidative stress and ceramide appearance at the erythroctye surface.

References

121

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide

Philipp A. Lang, M. Schenck, Jan P. Nicolay et al. · Nature Medicine · 2007 · 439 citations

, , +12

Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical associations

BL Wood, DF Gibson, JF Tait · Blood · 1996 · 434 citations · Full text

Role of Ca<sup>2+</sup>-activated K<sup>+</sup> channels in human erythrocyte apoptosis

Philipp A. Lang, Stefanie Kaiser, Swetlana Myssina et al. · American Journal of Physiology-Cell Physiology · 2003 · 381 citations

, , +18

Lysophosphatidic Acid Induces Thrombogenic Activity Through Phosphatidylserine Exposure and Procoagulant Microvesicle Generation in Human Erythrocytes

Seung-Min Chung, Ok‐Nam Bae, Kyung‐Min Lim et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2006 · 320 citations · Full text

Phosphatidylserine‐related adhesion of human erythrocytes to vascular endothelium

Christèle Closse, M Boisseau · British Journal of Haematology · 1999 · 313 citations