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Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer

Benjamin L. Maughan, Daniel L. Suzman, Brandon Luber, Hao Wang, Stephanie Glavaris, Robert M. Hughes, Rana Sullivan, Rana Harb, Karim Boudadi, Channing J. Paller,

Cancer Chemotherapy and Pharmacology · 2016 · 31 citations · 11 references

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11

Design and End Points of Clinical Trials for Patients With Progressive Prostate Cancer and Castrate Levels of Testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group

Howard I. Scher, Susan Halabi, Ian F. Tannock et al. · Journal of Clinical Oncology · 2008 · 2.2K citations · Full text

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

Sunil Karhadkar, G. Steven Bova, Nadia M. Abdallah et al. · Nature · 2004 · 941 citations

, , +12

Itraconazole, a Commonly Used Antifungal that Inhibits Hedgehog Pathway Activity and Cancer Growth

James Kim, Jean Y. Tang, Ruoyu Gong et al. · Cancer Cell · 2010 · 519 citations · Full text

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Repurposing Itraconazole as a Treatment for Advanced Prostate Cancer: A Noncomparative Randomized Phase II Trial in Men With Metastatic Castration-Resistant Prostate Cancer

Emmanuel S. Antonarakis, Elisabeth I. Heath, David C. Smith et al. · The Oncologist · 2013 · 178 citations · Full text

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NVP-LDE-225 (Erismodegib) inhibits epithelial–mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128

Rajesh Nanta, Dhruv Kumar, Daniel G. Meeker et al. · Oncogenesis · 2013 · 104 citations · Full text

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