Concepedia

Pharmacodynamic Targets

Pharmacodynamic Targets is a theoretical construct that identifies the critical concentration or ratio of an antimicrobial agent required at the site of infection to achieve a desired therapeutic effect while minimizing resistance development.

153

Publications

8.9K

Citations

1.2K

Authors

433

Institutions

Publications per year

2017–2026

67

Parents

Publications

153

DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current  -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

Jason A. Roberts, Sanjoy K. Paul, Murat Akova et al. · Clinical Infectious Diseases · 2014 · 1.1K citations · Full text

, , +17

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Jason A. Roberts, Carl M. J. Kirkpatrick, Michael S. Roberts et al. · Journal of Antimicrobial Chemotherapy · 2009 · 348 citations

, , +16

Selection of a Moxifloxacin Dose That Suppresses Drug Resistance in<i>Mycobacterium tuberculosis,</i>by Use of an In Vitro Pharmacodynamic Infection Model and Mathematical Modeling

Tawanda Gumbo, Arnold Louie, Mark R. Deziel et al. · The Journal of Infectious Diseases · 2004 · 317 citations

, , +17

A Phase I Pharmacokinetic and Pharmacodynamic Study of OGX-011, a 2′-Methoxyethyl Antisense Oligonucleotide to Clusterin, in Patients With Localized Prostate Cancer

Kim N., Elizabeth A. Eisenhauer, Ladan Fazli et al. · JNCI Journal of the National Cancer Institute · 2005 · 263 citations

, , +11

<i>In Vivo</i> Comparison of the Pharmacodynamic Targets for Echinocandin Drugs against <i>Candida</i> Species

David R. Andes, Daniel J. Diekema, Michael A. Pfaller et al. · Antimicrobial Agents and Chemotherapy · 2010 · 227 citations

, , +17

1–5 of 153

Authors

1.2K

  1. DP
    David P. Nicolau

    Hartford Hospital, United States

    12 publications · 620 citations

    11

    h-index

  2. JL
    Joseph L. Kuti

    Hartford Hospital, United States

    9 publications · 509 citations

    9

    h-index

  3. JA
    Jason A. Roberts

    The University of Queensland, Australia

    9 publications · 3.1K citations

    8

    h-index

  4. DR
    David R. Andes

    University of Wisconsin–Madison, United States

    8 publications · 644 citations

    8

    h-index

  5. AJ
    Alexander J. Lepak

    University of Wisconsin–Madison, United States

    6 publications · 448 citations

    6

    h-index

1–5 of 1.2K

Institutions

433

  1. Hartford Hospital

    Hartford, United States

    12 h-index

    25 publications

    1.2K citations

  2. University of Wisconsin–Madison

    Madison, United States

    8 h-index

    30 publications

    2.1K citations

  3. Hartford Financial Services (United States)

    Hartford, United States

    8 h-index

    15 publications

    890 citations

  4. The University of Queensland

    Brisbane, Australia

    8 h-index

    107 publications

    97.1K citations

  5. Duke Medical Center

    Durham, United States

    7 h-index

    15 publications

    1.1K citations

  6. University of Florida

    Gainesville, United States

    6 h-index

    27 publications

    1.1K citations

  7. Royal Brisbane and Women's Hospital

    Brisbane, Australia

    6 h-index

    16 publications

    7.4K citations

  8. Albany College of Pharmacy and Health Sciences

    Albany, United States

    4 h-index

    4 publications

    274 citations

1–8 of 433

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 27 publications · 1.4K citations

    19

    h-index

  2. Journal of Antimicrobial Chemotherapy

    JAC · 16 publications · 1.2K citations

    15

    h-index

  3. International Journal of Antimicrobial Agents

    6 publications · 172 citations

    6

    h-index

  4. Cancer Chemotherapy and Pharmacology

    6 publications · 244 citations

    6

    h-index

  5. 4

    h-index

1–5