Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation

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Medicine, Internal Medicine, Pharmacology +14

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

Sean B. Joseph, Antonio Castrillo, Bryan Laffitte et al. · Nature Medicine · 2003 · 1.1K citations

Life Sciences, Immunology, Molecular Biology +16

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Sunder Mudaliar, Robert R. Henry, Arun J. Sanyal et al. · Gastroenterology · 2013 · 915 citations

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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

Raffaella Maria Gadaleta, Karel J. van Erpecum, Bas Oldenburg et al. · Gut · 2011 · 851 citations

Life Sciences, Immunology, Pharmacology +17

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

Yan‐Dong Wang, Wei‐Dong Chen, Meihua Wang et al. · Hepatology · 2008 · 622 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17