RSC Advances · 2016 · 15 citations · 35 references
PharmacyBiomedical EngineeringOncologyChemotherapyDrug DeliveryNanoparticle Drug DeliveryCancer Drug DeliveryCancer NanomedicineNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicinePh-responsive Drug Delivery5-Fluorouracil Therapy5-Fluorouracil TreatmentCancer NanotherapyNanogelsPh-responsive DeliveryPh-sensitive NanoparticlesPhysiological Ph EffectsPolymeric Nanogels
The aim of the study was to develop 5-FU loaded pH and thermo-sensitive nanogels that could specifically respond to tumour endosomal pH and extracellular pH, while being dormant to physiological pH at physiological temperature.
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Acid pH in tumors and its potential for therapeutic exploitation.
Ian F. Tannock, Daniela Rotin · PubMed · 1989 · 1.6K citations
Medicine, Oncology, Pharmacology +16
Acidic extracellular microenvironment and cancer
Shigeyuki Ozawa, Chihiro Miyamoto, Yojiro Maehata et al. · Cancer Cell International · 2013 · 1.3K citations · Full text
Medicine, Cancer Biology, Oncology +17
Thermoresponsive Polymers for Biomedical Applications
Mark A. Ward, Theoni K. Georgiou · Polymers · 2011 · 1.1K citations · Full text
Natural Sciences, Biomedical Engineering, Materials Science +17
Younsoo Bae, Nobuhiro Nishiyama, Shigeto Fukushima et al. · Bioconjugate Chemistry · 2004 · 732 citations